544 CLINICAL VETERINARY MEDICINE AND SURGERY. 



injected on the 12th March, the other on the 12th April, with human 

 tuberculosis ; the first died on the 2nd July and the second on the 15th. 

 In both we found generalised visceral tuberculosis precisely like that 

 which follows inoculation with human tuberculosis. 



These experiments may be summed up as follows : — Six guinea-pigs 

 received avian cultures ; two died rapidly, without showing visceral 

 lesions on post-mortem examination; four resisted, three of which were 

 afterwards inoculated with human tuberculosis. The latter behaved 

 as though previously healthy. Without wishing to draw a final con- 

 clusion from these three experiments we think it allowable to conclude 

 that previous inoculation with avian tuberculosis neither favours nor 

 impedes the development of human tuberculosis. 



To summarise the facts established in this first portion of our 

 research, we have only to reproduce in their entirety the propositions 

 formulated at the end of our previous note on avian tuberculosis. 



Tuberculosis of Gallinacese is transmissible to fowls. Intra-venous 

 or intra-peritoneal inoculation is followed by the development of 

 generalised and rapidly fatal tuberculosis. 



The rabbit readily contracts avian tuberculosis, at least when 

 bacilli are introduced into the peritoneum ; death follows in two or 

 three months from generalisation of the infection. 



The guinea-pig, though more sensitive to human tuberculosis than 

 the rabbit, is much more resistant than it to avian tuberculosis. 

 Inoculation rarely produces general infection. In almost all the cases 

 (gi per cent.) either the animals show no lesion of tuberculosis (54 per 

 cent.), or they show, at the point of inoculation, a caseous abscess 

 which persists for a longer or shorter time (8 per cent.) ; or visceral 

 infection occurs (29 per cent.), the tubercles remaining partial and 

 discrete, and tending towards fibrous transformation and recovery. 



Part 2. — Inoculation of the Gallinacece with Mammalian Tuberculosis. 



Having shown the manner in which avian tuberculosis behaves 

 when inoculated into animals, it now becomes necessary to approach 

 the converse problem, and to discover if mammalian tuberculosis can 

 be conveyed to birds. 



We have already remarked that authors who have studied this 

 question are far from agreeing. Although Bollinger, Koch, and 

 Nocard were able to transmit human tuberculosis to the Gallinaceae, 

 the majority of pathologists have had negative results. Villemin, 

 H. Martin, Straus and Wurtz, Riffi and Gotti, Rivolta, Maffucci, 



