EXPERIMENTAL PRODUCTION OF TUBERCULOSIS IN PARROTS. 



571 



Having shown that tuberculosis of parrots is, or at least may be, 

 of human origin, the question arises whether the bacillus maintains its 

 virulence in the organism of these birds. We have endeavoured to 

 answer this question by directly inoculating with bacilli obtained from 

 several parrots. We took care not to grow the virus on artificial media, 

 for culture notably modifies its pathogenic properties ; we wished to 

 determine the virulence of the original bacilli. 



The two following tables summarise two series of inoculations, the 

 first of which was started with caseous material contained in the 

 centre of a tuberculous swelling of the wing (Case 11), the second 

 with a horny growth occupying the right side of the face (Case 5). 



EXPERIMENT IV. 



P.\KROT. 



Titberculoiis growth on the wing. 

 April nth* 1894. 



GUINE.\-PIG. 



Died May 26th (45 days). 

 Tubercle at point of inoculation ; tubercu- 

 losis of the peritoneum and liver. 



Guinea-pig. R.^bbit. 



Died June i8th (23 Killed Novem- 



days). 



Tuberculosis of the 



peritoneum, liver, 



and spleen. 



I 



Guinea-pig. 



Died October 15th 



(99 days). 

 Generalised tubercu- 

 losis, spleen, liver, 

 and lungs. 



ber 7th (162 

 days). 

 A few gramda- 

 tions on the peri- 

 toneum and in 

 the liver. 



Guinea-pig. 

 Died May 29th (48 days). 

 Tubercle at point of inoculation ; general- 

 ised tuberculosis* {peritoneutn, liver, 

 spleen, and lungs). 



Guinea-pig. Guine.a-pig. Rabbit. 



Died September Died October Killed September 

 29th (123 days). 26th (144 days). 23rd (117 days). 

 Generalised tu- Generalised tu- A few granulations 

 berculosis. bercitlosis. on the peritoneum 



and in the liver. 



* We have rarely witnessed such a development of tubercles ; the peritoneum was 

 covered with granulations, the spleen enlarged tenfold, and the liver was crammed with 

 nodules. The lungs contained innumerable large tubercles, particularly in the posterior 

 lobes. The mediastinal and mesenteric lymphatic glands were enlarged and caseous. 

 Microscopic examination showed all the affected organs and tissues to contain numerouii 

 bacilli. 



