INTRA-VENOUS INJECTIONS OF IODINE. 609 



body-weight, in the saphenous vein. In a quarter of an hour it showed 

 signs of restlessness and whined a Httle. Twenty minutes later slight 

 localised intermittent trembling occurred, and gradually became 

 accentuated and generalised. The trembling fits afterwards dimin- 

 ished, and finally disappeared at the end of four hours. At 8 p.m. the 

 animal showed no disturbance and readily ate. During the night 

 urine resembling that of hemoglobinuria was passed. 



(4) A dog, weighing 30I lbs., received at 10 a.m. on the 24th Feb- 

 ruary an injection of three fluid drachms of a 5 per cent, iodine 

 solution ("3 grain per pound of body-weight) in the jugular vein. In a 

 few minutes faeces were passed. Except for signs of restlessness no 

 manifest disturbance ; only a few shivering attacks. During the 

 afternoon the dog passed blackish haemoglobinuric urine ; no after- 

 symptoms. 



(5) A goat, weighing 81^ lbs., received at 2 p.m. on the 25th Feb- 

 ruary in the jugular vein an injection of seven fluid drachms of a 5 

 per cent, iodine solution ('26 grain of iodine per pound of body- 

 weight). Temperature before injection 39*2° C. At 3 p.m. masti- 

 catory movements were made. At 4 p.m. slight trembling of the 

 muscles of the quarter and thigh, passage of haemoglobinuric urine. 

 At 6 p.m. temperature 40"6° C. ; prostration ; the trembling attacks 

 persisted. At 8 p.m. temperature 40*2° C. ; fresh passage of haemo- 

 globinuric urine. After this the symptoms gradually disappeared. 



(6) A cow, weighing 620I lbs., received at 9 a.m. on the 25th Feb- 

 ruary an injection into the jugular vein of two fluid ounces of a 5 per 

 cent, solution of iodine ('07 grain per pound of body-weight). At the 

 end of fifteen minutes, salivation ; twenty minutes later, passage of 

 normal faeces and yellowish urine ; no manifest disturbance of circu- 

 lation or respiration. At 3 p.m. slight trembling attacks in the hind 

 quarters, continuing for two hours ; hyperthermia, which attained its 

 maximum (i"4° C.) at the eighth hour. At 4 p.m. passage of brownish 

 haemoglobinuric urine. During the night the symptoms disappeared. 



(7) A horse, weighing 525J lbs., received at i o'clock on the 28th 

 February an injection of eleven fluid drachms of a i per cent, iodine 

 solution. At the end of a few minutes fa;ces were passed: Half an 

 hour later trembling appeared, at first localised in the hind limbs, but 

 soon becoming generalised ; it diminished rapidly, and disappeared in 

 an hour. 



At 2 p.m. next day received an injection of thirteen and a quarter 

 fluid drachms of the same solution. Immediately before injection 

 temperature 39*3° C, respirations 12, pulse 45. Faeces were passed at 

 the end of three minutes. 12.30 p.m., trembling movements in the 



