20 METHODS OF ELUCIDATING DISEASE. 



tliat experience with a large grasp of facts and correct inter- 

 pretation of symptoms is needful. While it is not to be 

 forgotten if these do not exist, or their interpretation is specially 

 difficult, that a statement of eventualities may be all which 

 we are warranted in giving. If, on the contrary, there is 

 evidence for forming a definite opinion, this ought to be stated 

 plainly, and with the confidence which the evidence before us 

 entitles us to do. 



III. The Nature, Locality, Form, and Course of 



Development of Disease. 



Under these considerations we have to regard — 



1. The particular and strange activities we call disease, in 

 their general and particular manifestations and their relations 

 to normal conditions ; not merely their deviations from what 

 is recognised as health, but the manner of such deviations, 

 with the probable influences which may result from the opera- 

 tion of such activities. 



2. The localizations of these disturbances and the structures 

 invaded, the changes in form or manifestations which these 

 assume under the varying and diversified influences to which 

 they are subject, and under which they advance or recede, all 

 tending to the production of those modifications in diseased 

 processes known as types or variations. 



3. The complications which, although appearing at the same 

 time, are not necessarily part of the recognised clinical pheno- 

 mena, and the textural changes and ultimate impairment of 

 functional activity known as sequelae. 



IV. Textural Alterations the Kesult of Disease. 



Here we learn through examination of the impress left by 

 the abnormal activities, these modified health processes, more 

 of the nature and character of the changes we recognise as 

 disease. Under the examination of the result of these activities, 

 the anatomy of disease, are grouped all which we may learn by 

 macroscopic, microscopic, or chemical examination of their 

 conditions and change. While by pathological histology we 

 take cognizance of the growth, development, decline, or change 

 of those elementary structures wliich these unnatural activities 



