ANATOMICAL CHARACTERS. 121 



soften, and suffer fatty and calcareous metamorplioses, this 

 alteration proceeding from the centre to the circumference of 

 the growth. These nodules seem to possess an irritating action 

 on the surrounding textures amongst which they are situated, 

 for they are generally accompanied with inflammation and 

 infiltration of a gelatinous or hyaline character, while occasion- 

 ally they are practically encircled by a fibrous capsule, which, 

 however, is not perfectly distinct from the nodule itself. In 

 some instances this inflammatory and exudative process from 

 its extent is spoken of as the ' pneumonia of glanders.' It is 

 of the lobular character. These nodules are scattered through- 

 out the entire substance of the lungs. 



In cutaneous glanders or farcy, the nodules or growths are 

 found in the cutis and subcutaneous connective tissue. The}' 

 are not sharply defined, are of different sizes, and in their 

 manner of growth and intimate structure resemble those 

 situated in the lungs and nuicous membranes. They also take 

 on disintegration and form ulcerous sores. 



The lymphatic vessels are enlarged as the result of inflam- 

 matory action, they contain a yellowish purulent liquid, and 

 are knotted, or possess numerous bulgings, throughout their 

 course. The glands with which these vessels are connected 

 may not be much enlarged ; they are, however, indurated and 

 distinctly nodulated. 



In the infiltrated forms of its development there may be few 

 tubercles, but instead, we observe swelling and infiltration of 

 the mucous membrane, with death and removal of its epithelium 

 in granular masses. This is to be looked for chiefly in the 

 membrane of the nasal passages ; the infiltration, however, 

 occurs also in the lungs. In very few cases of glanders will 

 the lungs be found perfectly healthy or free from the lesions 

 of existing nodules or specific infiltration. BolHnger mentions 

 that in fifty-two carefully examined cases the lungs were per- 

 fectly sound in only four. When other organs, as the liver, 

 spleen, or kidneys, as well as the voluntary muscles, become 

 the seats of the specific growths of glanders, and wherever 

 these are found, the same general and special characters are 

 associated with them, and the same tendency to elemental 

 disintegrative changes. 



Incubation, Symptoms, etc. Incubation. — Like all other 



