INCUBATION — SYMPTOMS. 125 



which, as well as the floor of the pit or ulcer, are inclined 

 to nodulate and become covered with prominent and very vas- 

 cular granulations. 



These ulcers or sores are not disposed to heal, but extend, 

 and by the removal of the septa or sound tissue existing be- 

 tween several small sores, one large rodent ulcer is produced, 

 and should the animal survive long enough, we may have ne- 

 crosis and penetration of the septum nasi. 



When these lesions have existed on the nasal membrane for 

 even a short time, or probably contemporaneously with their 

 appearance, the larynx and membrane of the sinuses of the 

 head become similarly affected. 



The nasal discharge, which at the beginning of the fever 

 may have only slightly differed from that of a common 

 catarrh by being of a yellowish colour and slightly viscid, be- 

 comes, on the development of the papules into ulcers, thick 

 and mingled with puriform matter, and as erosions advance 

 and capillaries are ruptured is sanguineous, more copious, and 

 sometimes flaky. The neighbouring lymphatics and lymphatic 

 glands become swollen, specially those in the intermaxillary 

 space, sometimes only on one side, occasionally on both, de- 

 pending upon the fact whether both or only one nasal cavity 

 is involved. At first the o-land-structures and surroundinsf 

 textures feel soft and slightly painful, as if they might suj^pu- 

 rate, which they rarely do ; shortly this enlarged condition be- 

 comes better defined, harder, and less painful. 



Generally, in this condition of ulcerated nasal membrane 

 and tumified lymphatic glands, there is the accompaniment of 

 swollen or corded lymph vessels, those passing between the 

 nose and mouth to the glands in the maxillary space be- 

 coming distinctly marked out, corded, nodulated, and ulcerated. 



The scalp, face, and particularly the structures around the 

 nose and mouth, become cedematous, while the farcied and in- 

 flamed state of lymph vessels is not confined to the head and 

 face, but extends to the extremities, on which, in the course of 

 the swollen lymphatics, tubercles or nodules develop them- 

 selves, which after a time soften, disintegrate, and discharge 

 purulent matter. 



The breathing, if not snuffling and hoarse from the outset, 

 very shortly becomes so, partly owing to the oedema of the 



