130 GLANDERS AND FARCY. 



a clear white colour, with well-marked fibrous bands either 

 branching off from one main band where the cavity has been 

 extensive, or crossing each other stellate fashion, where the 

 ulcers or sores have been less extensive. 



Sometimes, when thus healing, a glanderous sore of a little 

 more penetrating character may still be left open, yet to 

 undergo the healing process, while the remainder is covered 

 with fibroid cicatricial tissue. 



These specific cicatrices and callosities of fibroid tissue 

 represent, therefore, ulcers or erosions that have actually 

 healed. 



These, Bollinger remarks, ' occur exclusively in the chronic 

 form of glanders ' — the only cases I have seen were in such — 

 and he states that they were first accurately described by 

 Leisering, whose views on this point were corroborated in the 

 main by Virchow, the latter differing from Leisering in this 

 respect only, that he admitted the possibility of genuine 

 specific cicatrices being formed from ulcers, whereas Leisering 

 maintained that the cicatrices produced by the infiltration and 

 development of fibrous tissue were not to be regarded as 

 evidence of the healing of specific lesions, but merely as a 

 specific form of neoplastic growth concomitant to the disease. 

 From all, however, which I have observed myself, and from 

 what I am able to glean from those whose experience on this 

 point is considerable, I am disposed to regard this production 

 of cicatricial tissue, whether found in connection with specific 

 ulcers, the result of softened nodules, or of infiltration, as the 

 evidence of a healthy healing and reparative process in con- 

 .nection with these specific sores. 



Although I freely allow thus much, I would at the same 

 time caution all Avho may observe this action in connection 

 with the glanderous sore, and who are intimatel}'^ associated 

 with such cases of the disease, not to be misled with the idea 

 that the appearance of cicatrization of the ulcers is evidence 

 or indication of restoration of systemic or general healthy 

 functional activity. 



It ought ever to be remembered that these ulcers or sores 

 on the nasal membrane may most certainly heal or cicatrize in 

 the way indicated, and still the specific dyscrasia remain ; that 

 it is highly probable that even with this local heahng process 



