SYMPTOMS OF CHROXIC GLANDERS. 131 



there may exist in the hmgs, as previously, the specific nodules 

 and tubercles characteristic of the disease of which these 

 local nasal sores now healed are but partial manifestations and 

 exhibitions of the peculiar general diseased condition, and that 

 it is almost certain, should the animal survive lono- enousfh, 

 that these local sores will again appear. 



The certainty also that in such cases, even with the cica- 

 trization of the chancres, the power of infection is not lost, 

 that from such an animal an acute case of glanders may be 

 propagated, must ever be kept before our minds, so as to regu- 

 late our conduct and the advice given. 



h. Changes connected luith the Lymphatic Glands and 

 Lymphatic Vessels. — Concomitant with the phenomena taking 

 place in the nasal chambers are the changes encountered in 

 connection with the lymph-glands situated in the inter- 

 maxillary space. In the swelling and induration of these 

 structures there is a distinct symmetrical accordance with the 

 situation of the lesions of the nasal cavities. When the 

 nodules or ulcers exist in both chambers, the gland-structures 

 of both sides are affected. When only one cavity — usually 

 the left— is the seat of the lesion, the glands of that side 

 only are involved. 



When participating in the morbid processes going on in the 

 course of the development of the disease, these structures 

 first become full and enlarged, partly from infiltration in the 

 true gland-structures, but chiefly from the same condition 

 occurring to the surrounding connective tissue amongst Avhich 

 they are placed. AVhen both glands are affected the swelUng 

 is at first most distinctive in the middle of the sub or inter- 

 maxillary space ; and whether one or both are the seat of the 

 morbid action, the feeling is at first of a soft and doughy 

 character, attended with a trifling amount of pain. Gradually 

 this soft swelling is rej)laced by a condition of greater firmness 

 and less sensibility, while with the disappearance of the 

 doughy feeling we have the establishment of the distinct 

 nodulated condition, which is persistently maintained. The 

 swelling, whether of one or of both glands, is more marked as 

 increasing the bulk of the gland antero-posteriorly than across 

 the space. 



AVith the acquirement of the nodulated condition we also 



9—2 



