136 GLANDERS AND FARCY. 



nodules, or buds, in connection with the skin and subjacent 

 tissues, whicb after a time soften and ulcerate, leaving an un- 

 healthy open sore discharging a puriform liquid, and not dis- 

 posed to heal. 



The situations in'which these tumours are encountered are 

 various, a preference being shown for those localities where 

 the skin is thin and vascular, as over the facial, the maxillar}', 

 and laryngeal regions, along the sides of the neck, inferior 

 parts of the chest, inside the fore-arms, along the belly, over 

 the flanks, and inside^the thighs. 



These tumours vary in size, like the same growths in acute 

 farcy ; and like them*also,''they vary in a similar manner as to 

 the exact seat of their development. 



The smaller are usually situated in the cutis, are more 

 numerous, more generally distributed over the body, and in 

 any particular locality where they occur they are more given 

 to coalesce after ulceration and suppurative action have been 

 established. The larger are chiefly confined to the sub- 

 cutaneous connective tissue, and frequently only involve the 

 slvin when undergoing the softening and ulcerative process. 

 They are also less numerous, not so disposed to be closely 

 grouped together over circumscribed surfaces, and conse- 

 quently less apt to become confluent. In chronic farcy we 

 may sometimes see certain of the nodules or swellings which 

 seem distinct enough, and likely to proceed to perfect develop- 

 ment, retrogress, or at least remain perfectly indolent for a con- 

 siderable time, and finally disappear. 



The course of their appearance and development varies much. 

 They may appear in an isolated order over difterent parts of 

 the body at the same, or nearly same, time ; or a few may first 

 make their appearance, remain for a few days isolated, to be then 

 joined by a fresh eruption of papules over some particular 

 part, or even distributed over the greater portion of the body. 

 In this latter case they are most probably of small size. The 

 greater number of the nodules in chronic farcy are not much 

 elevated above the surface of the surrounding skin ; they are, 

 however, as a rule, more sharply defined than the similar 

 growths in the acute form, the accompanying infiltration of 

 the meshes of the connective tissue being less extensive, and 

 shading ott' at the base of the tumour less gradually than in 



