56 Veterinary Medicine. 



tion has subsided, constituting an indolent or cold abscess. When 

 the imprisoned pus is inclosed by thick fibrous or resistant tissues 

 at all points but one, it will make its way along the narrow pas- 

 sage of yielding tissue, but as the resulting outlet is constricted, 

 long, and tortuous, the contents cannot readily escape through it 

 nor the walls of the abscess contract so as to expel the confined 

 pus, and the latter goes on forming and discharging through the 

 narrow outlet for months or years. This is a fistula or sinus. 



Healing by Adhesion or First Intention. When a clean- 

 cut wound has the blood staunched and its lips brought together 

 without exposure to the air (or contact with pyogenic germs), 

 they adhere at once and heal without pus or almost any apprecia- 

 ble formation of new tissue. Here the lymph thrown out on the 

 cut surfaces agglutinates them, and the cells, multiplying, form a 

 thin layer of embryonic tissue which gradually develops into a 

 fibrous structure and repairs the breach without any perceptible 

 scar. 



Healing by Second Intention. Granulation. When a 

 wound has caused destruction of tissue, or when a simple incision 

 is left exposed to the air, the breach is filled up by new tissue 

 through the process known as granulation. The superficial layer 

 of lymph thrown out on the raw surface becomes oxidized and 

 degenerates into pus, while the deeper layers become solid, fibril- 

 lated, the seat of cell-growth, and are finally transformed into a 

 fibrous structure. New blood-vessels form in loops in the devel- 

 oping lymph and constitute the bright-red granulation-points 

 which cover the raw surface. The fibrous tissue into which the 

 lymph is transformed undergoes gradual contraction in develop- 

 ment, and thus, day by day, the edges of the adjacent healthy 

 skin are drawn in. so as to cover the wound more or less per- 

 fectly, and a slight scar only is left when healing has been 

 accomplished. 



Granule Corpuscles and Masses. This is another de- 

 generative transformation in lymph and, is seen mainly in in- 

 flamed glands and brain and lung-tissue. The cells found in the 

 exuded lymph are made up of granules t¥to¥ i^^^h in diameter, 

 and besides these, large, irregularly shaped masses of granules 

 are extended along the capillary blood-vessels. After the lymph 

 has coagulated these granular masses soften and liquefy prelimi- 



