532 Veterinary Medicine. 



Giirlt, Briickmiiller, Kitt and others. From the walls of the 

 gall bladder it grows in pyriforni masses, and on the surface and 

 in the interior of the liver, it may appear as hard, cancerous 

 masses of all sizes. 



Epithelioma . This has been described by Kitt, Martin, Blanc, 

 Ivcblanc, Morot, Cadeac, and Besnoit. It appears in masses 

 varying in size from a millet seed up, l)ulging from the surface of 

 the organ or deeply hidden in its substance, and stained 3'ellow or 

 green with bile. The liver is usually enlarged, amounting to 

 even 34 pounds (Cadeac). The formation connnencing in the 

 acini invades all surrounding parts causing compression and 

 atrophy of the liver cells, and the formation of nests of epithelioid 

 cells often with multiple nuclei and nucleoli. Cirrhosis is not un- 

 common, and fatty and other degenerations. Microbic invasion 

 and necrobiosis are also common. 



NEOPIvASMS IN THE SHEEP'S LIVER. 



Ade7ioma has been met with by McFadyean, Johne, Kitt and 

 Bollinger. They hung as pediculated tumors from the surface of 

 the liver, and were in part wedged into its substance displacing 

 the hepatic tissue and vessels. In general they consisted of a 

 dense fibrous stroma with cylindroid and biliary cells in great 

 abundance, sometimes arranged in tubular form. Specimens 

 described b}^ Kitt and Bollinger attained to the size of a man's 

 head and were stained of a deep green color. 



Carcinoma. Casper reports a ca.se of hepatic cancer in the 

 sheep .secondary to cancer of the mesentery. 



