130 Veterinary Medicine. 



intervals of temporary recovery correspond to the subsidence of 

 hyperaemia and the reabsorption of the liquid portion of the 

 exudate. The manifestations during an access correspond directly 

 to those met with in encephalitis. As in that affection there is 

 usually an initial period of excitement and functional nervous dis- 

 order tending to more or less somnolence, stupor, paralysis or 

 coma, with long intermissions of apparently good health. In other 

 cases the stupor or paretic symptoms may persist up to the fatal 

 issue. 



MELANOMA OF THE ENCEPHALON. 



Black pigment tumors have been found in connection with the 

 brain and especially the meninges, varying in size from a pea to 

 a walnut, and as a rule, secondary to similar formations else- 

 where. They are most common in gray horses which have 

 turned white, and may give rise to gradually advancing nervous 

 disorder. Bouley and Goubaux record a case of this kind at- 

 tended with general paralysis. W. Williams reports the case of 

 an aged gray stallion with melanomata on the meninges and in 

 the brain substance which were associated with stringhalt of old 

 standing. Mollereau in a vertiginous horse found a pigmented 

 sarcoma in the right hemisphere between the gray and white 

 matter, and like an olive in size and shape. There were melano- 

 mata around the anus. (Annalesde Medecine Veterinaire, 18S9). 

 So far as such have been examined they follow the usual rule in 

 melanomata in having a sarcomatous structure. 



While it is impossible to make a certain diagnosis without 

 opening the cranium, the condition may be suspected, in gray 

 horses, when melanotic tumors are abundant in the usual ex- 

 ternal situations (anus, vulva, tail, mammae, sheath, lips, eye- 

 lids, etc.), and when brain .symptoms set in and progress slowly 

 in such a way as to suggest the gradual growth of a tumor. 



Treatment is hopeless, since if they have invaded the brain, 

 the tumors are likely to be multiple in the organ, and numerous 

 and vvidelv scattered elsewhere. 



