386 Veterinary Medicine. 



ence of the particular infective disease are characteristic. In 

 cases due to debility and marasmus the disease may appear with 

 little indication of attendant irritation, lachrymation, tenderness, 

 photophobia, or even opacity. At one circumscribed point only 

 is there a grayish cloud, perhaps no more than a thirtieth of an 

 inch in diameter, and slightly projecting. This becomes soft 

 and gelatinous and finally drops off, leaving a shallow excavation 

 or abrasion, surrounded by a narrow grayish zone. This ne- 

 crobiosis may extend inward and even penetrate the membrane, 

 before the lesion has enlarged to more than a hemp seed in diam- 

 eter. In other cases lateral extension occurs. 



It is always important to recognize the ulcer at an early stage, 

 and this may be done by oblique focal illumination and the use 

 of a magnifying lens. In case of doubt a drop of solution of 

 fluorescin placed on the cornea and at once washed out, will 

 promptly reveal the lesion by the high color given to the tissues 

 which have been denuded. 



When perforation has taken place the membrane of Descemet 

 may bulge out of the orifice and undergo granulation, or it may 

 open and allow the escape of the aqueous humor. Active kera- 

 titis and even panophthalmia are liable to follow perforation. 

 Again, the escape of aqueous humor tends to the approximation 

 or contact of the iris with the cornea, where it may become ad- 

 herent and staphyloma may ensue. 



Prognosis is unfavorable in debilitated subjects, and when the 

 lesion is extensive and in the line of vision. In slight recent 

 cases in good constitutions it is favorable. 



Treatmejit. Debility must be met by tonics and rich diet, 

 fresh air, sunshine and exercise. Specific diseases must be met 

 according to their nature. 



Locally the daily application of silver nitrate lotion (i : 200) is 

 often very effective, proving an excellent antiseptic, checking the 

 microbian proliferation, and coagulating the albumen in the 

 wound so as to form an antiseptic barrier to further invasion. A 

 mercuric chloride solution (1:5000) is an excellent substitute. 

 Iodoform powder though less antiseptic, is especially valuable in 

 favoring the healing process. It is dusted over the cornea, and 

 the upper lid immediately drawn down and held over the cornea 

 for several minutes. If this is neglected the dry powder is re- 



