130 Veterinary Medicine. 



coagulate with undue readiness and firmness, The pharangeal 

 and intermaxillary lymph glands are red and congested in their 

 outer zone. 



In the more severe cases the alterations in the blood are perhaps 

 the most constant of the morbid features. The blood is fluid and 

 incoagulable, or the clot is soft, diffluent and black, the red 

 globules are crenated or broken up, and show little tendency to 

 adhere in rouleaux. The escaped haematoidin accumulates in 

 masses in the serum in crystalline forms, giving it a high stain- 

 ing power when a line is drawn with it on white paper. Fatty 

 globules also float in the mass. The leucocytes are relatively ver3 r 

 much encreased and the red globules diminished Dieckerhoff 

 found 30,000 and Trasbot 40,000 leucocytes in a cubic millimetre. 



The difHuence is not constant. Blood drawn in the earlier 

 stages of the disease, coagulates with extraordinary firmness, in- 

 fluenced, doubtless, by the encrease of the leucocytes, the disin- 

 tegration of the blood globules, and the liberation of globulins. 

 This serves also to partially explain the early and sudden deaths 

 from coagula in the heart and large vessels, which are occasionally 

 met with. Such clots in the heart are often found adherent to 

 the valvular or ventricular endocardium which at such points 

 shows cloudy swelling, thickening, cell proliferation and even 

 encreased vascularity and granular elevations. 



In advanced cases, however, the prominent features are usually 

 acidity, blackness, and incoagulability of the blood, its resistance 

 to oxygen, altered and broken down red globules, free coloring 

 matter, relative encrease of white cells, and, if necropsy has been 

 delayed, the abundance of septic microbes (cocci and baccilli). 

 Petechiae are abundant on the serosae especially on the pericar- 

 dium. 



Lesions of the alimentary mucosa are very constant. There 

 may be stomatitis, with tumid follicles and even ulcers (Kowa- 

 lavsky). In the stomach the right sac has its mucosa thickened, 

 softened, red, congested, petechiated and discolored. The sum- 

 mits of the folds may be ulcerated (Labat). Similar lesions are 

 presented in the small intestines. The agminated glands may 

 show many rounded elevations, with or without open discharging 

 follicles. The mucosa is covered with a mucopurulent material. 

 Otherwise, the small intestines, like the stomach, are usually empty. 



