Glanders. 237 



discharge from the nose, at first serous, with a remarkable vis- 

 cidity which tends to glue together the long hairs or even the 

 margins of the nostrils. This discharge may be reddish, green- 

 ish, or brownish and may become distinctly purulent and opaque. 

 The alee nasi are swollen, hot and painful, and the mucosa red, 

 congested, thickened, with a blackish or violet tint especially along 

 the median part of the septum ?iasi. On these, violet patches 

 appear on the second or third day, pronounced elevations of very 

 varying size indicating the centres of active hyperplasia. They 

 are usually yellowish or grayish, surrounded by a deep violet 

 areola, and may become confluent forming patches. The centre 

 of each undergoes rapid degeneration, forming a rounded ulcer 

 with salient edges, a yellowish base, more or less pointed or 

 streaked with red, and a viscid sero-purulent or bloody discharge 

 which may concrete in crusts or scale. The whole septum may 

 become one continuous ulcer with excavations of various depths 

 surrounded by hyperplastic elevations, and involving not only 

 the mucosa, but even the cartilage and leading to perforations. 



From an early stage of the attack the submaxillary lymphatic 

 glands and the investing connective tissue become swollen, form- 

 ing a mass of firm bean- or pea-like nodules, with no excessive 

 heat nor tenderness, and with little disposition to suppurate and 

 discharge. If this has lasted for some time the glands often be- 

 come more firmly attached to adjacent parts (maxilla, tongue) 

 by the contraction of the exudate. 



The swelling of the alse nasi also often extends to the skin of the 

 face, and firm, rounded cords formed by the swollen lymphatics 

 stretch upward toward the eye, or the submaxillary glands. 

 Upon the turgid lymphatics may appear more or less rounded 

 nodules from the size of peas to hazel nuts, which, unlike the 

 submaxillary glands, tend to soften, burst and discharge a viscid, 

 glain^, sanious liquid. 



At the same time the morbid process is liable to show itself in 

 the cutaneous lymphatics of one limb, usually a hind one, in the 

 form of firm cords, with degenerating or ulcerous nodules (farcy 

 buds) and pasty patches. Or the throat or lungs may become 

 involved, with local swellings, violent cough, dyspnoea and fever. 

 The swellings of the cutaneous lymphatics usually follow the 

 course of the veins, in the hind limbs the branches of the saphena, 



