320 Veterinary Medicine. 



appetite and rumination. Tenderness of the feet is shown by 

 halting or lameness and by the extension backward and shaking 

 of the hind feet in turn. 



With the appearance of the eruption, usually on the second 

 day of illness, the fever as a rule moderates, and on examination of 

 the mouth bullae of yid. to i inch in diameter may be found on the 

 inside of the lips, and cheeks, or on the palate and tongue, with, 

 in many cases, a congested areola, but showing no nodule as in 

 variola. These bullae may extend to the muzzle, pituitary mem- 

 brane or pharynx. They burst very soon after their formation, 

 exposing a red base of inflamed corium, with a clearly rounded 

 margin, or, at first, with shreds of the torn epithelial covering. 

 The salivation now becomes more profuse, glairy and even 

 bloody, and there is more active movement of the tongue. When 

 the bullae have been confluent there are formed extensive red 

 patches denuded of epithelium, and the suffering causes a com- 

 plete but temporary dysphagia. The renewal of the epithelium, 

 however, takes place promptly and may be well advanced in four 

 or five days. Upon the teats the bullae appear at about the same 

 time but are usually smaller than the buccal, and do not show the 

 thickened base of cow pox. The} 7 burst in 36 to 48 hours unless 

 broken earlier by the hands of the milker, forming sores com- 

 parable to those of the mouth, which are liable to be kept up by 

 the necessary manipulations in milking. 



Upon the feet the eruption shows especially in the interdigital 

 space, at first as vesicles smaller than those of the mouth and 

 teats, leaving erosions and ulcers which extend under the adjacent 

 horn, and upward on the front and back of the pastern. From 

 exposure to mud and filth these are liable to be kept up even 

 longer than those of the mouth and teats, and under neglect the 

 entire hoof is often shed. In sheep and swine the disease may be 

 localized almost exclusively in the feet. Sheep will even walk on 

 the knees. 



In young animals and those fed on the milk, the eruption may 

 take place on the intestinal mucosa with violent congestion, diar- 

 rhoea and a fatal issue. Aggravated cases may show gangrenous 

 mammitis or abortions. 



Mortality and Prognosis. While there are seasons of special 

 pathogenic severity, yet as a rule, the foot and mouth disease is 



