Dourine. 525 



Mare. In the mare in addition to the lesions of the internal 

 organs and blood, the following may be noted in connection with 

 the generative system. Phlegmonous or oedematous swellings, 

 sores or ulcers on the lips of the vulva, and on the vulvar and 

 vaginal mucosae. The parts become variously distorted, and the 

 vulva, habitually open may expose the swollen and ulcerated 

 clitoris. A crop of papules or vesicles, running into sores or 

 ulcers may appear on the urethral orifice, the vulva and adjacent 

 skin, and even though overlooked, their seats are marked later 

 by loss of cutaneous pigment and the formation of small white 

 spots. The mammae are sometimes inflamed, oedematous and 

 tender, with suppurative or necrotic foci and the adjacent lymph 

 glands are enlarged by infiltration or contracted by sclerosis. 



Dog. These resemble those in horses. In the bitch genito- 

 urinary congestion, inflammation and catarrh, subcutaneous in- 

 filtration under the belly and inside the thighs, swelling of the 

 inguinal lymph glands, emaciation, and pallor and atrophy of the 

 voluntary muscles are marked features. 



Symptoms. Horse. Incubation may last from one to eight 

 weeks (Maresch), but is usually 11 days from the infecting 

 service. It may be abridged by a special susceptibility, and by 

 repeated infections and hence the more acute cases are especially 

 seen in the male in daily service. In some such subjects local 

 genital infiltrations are speedily followed by paralysis or vertigo 

 which cuts off the patient in a few days. 



More commonly the malady is chronic though varying in 

 different countries, epizootics or even in particular cases. 



The first symptom is slight swelling of the anterior border 

 and raphe of the sheath, which gradually extends backward to 

 the scrotum and inguinal region and forward on the abdomen it 

 may be as far as the brisket. This may be hot and painful, but 

 is usually oedematous, cool and painless. The infiltration affects 

 the end of the penis, the meatus may be red and angry with a 

 slight muco-purulent discharge, and red spots vesicles and ulcers 

 may stand out clearly on the pigmented surface. Williams never 

 saw such eruptions in the American cases and doubts their exist- 

 ence except as the result of injuries. There are frequent semi- 

 erections and service is still possible. Later the engorgement ex- 

 tends to the specially pendent testicles, inguinal glands and others 



