Infective Ulcerative Vulvitis. 651 



suit was an open knee joint in one subject, the result of bruises 

 sustained before Dr. Childs arrived. His treatment was 5^ oz. 

 of the iodide at once, and 1 to 2 drs. every hour or second hour, 

 according to the size of the animal and the severity of the case. 



In other hands this medication has been less successful, which 

 may well be explained by the violence of the attacks, and the 

 lack of absorption from the inactive stomach. Unless it passed 

 on to the duodenum, it would be utterly useless, and hence the 

 exhibition by the rectum or subcutem might be tried. The 

 parallelism of the treatment of the two diseases of the plethoric 

 and possibly infected subject, — parturient paresis and haemoglo- 

 binaemia, — is striking, and it does not seem that the iodide treat- 

 ment should be abandoned because of a few unsuccessful cases. 

 Whether the iodide acts mainly as a microbicide, a chemical anti- 

 dote to toxins, an eliminaut, or a nerve sedative, or in two or 

 more of these modes, is unknown, but it would be rational to ex- 

 pect good results along one or more of these lines. Iodide treat- 

 ment should supplement, not supersede, the methods formerly in 

 use. 



INFECTIVE ULCERATION OF ANUS AND VULVA IN CATTLE. 



This curious affection is recorded as having prevailed in the 

 winter of 1897-8 in different localities in Iowa, Missouri, Kansas 

 and Nebraska. In 1900 and 1901 it was again reported in differ- 

 ent parts of Iowa. 



Causation. No bacteriology of the disease has been given, and 

 its appearance in isolated herds which had no known communi- 

 cation with other herds, and even in the young cattle on a farm 

 to the exclusion of the older ones, seems to suggest an enzootic 

 origin, perhaps in food or water, or in some toxin determined by 

 a fermentation of organic matter out of the body. 



On the Rodkey farm at Blue Rapids, Marshall county, Kan., 

 eight heifers from ten to fourteen months old, suffered, while the 

 seventeen steers of the same age and the milch cows escaped. 

 (Steddom). Near Shelby, la., a bull, from a healthy herd, 

 broke into an affected herd and served cows there, and was after- 

 ward returned to his own herd and served cows there, but did 

 not communicate the disease. (S. T. Miller). No case is re- 

 corded to show that any bull serving affected cows or heifers con- 

 tracted ulcer or other disease of sheath or penis. 



