25 



not occur even in advanced cases ; however, when it 

 is involved, the gland may be somewhat indurated and 

 stiff from suppurative inflammation either affecting it or 

 the surrounding tissues, but it is generally movable and 

 seldom or never fixed to the jaw and knotty as in glanders. 



In cases where the conjunctiva is the original seat 

 of the disease, no symptoms may be noticed externally 

 for several weeks after the disease has begun to 

 develop ; but as it spreads towards the edge of the eye- 

 lid, a slight watery or purulent discharge may be the 

 first thing detected, and on examination of the con- 

 junctiva a pale pink, flat, fungoid granulation will be 

 discovered under one of the lids or on the membrana 

 nictitans — varying in size according to the age of the 

 lesion. In one case (Plate XVII) which I observed, 

 the granulation was about the size of the top of a pencil 

 when first noticed, and there was no discharge or 

 outward symptom of the disease for weeks, and it could 

 only be seen when the eyelid was forcibly inverted. 

 As the case developed the granulation spread ; as 

 soon as it began to protrude beyond the edge of the 

 eyehd the other symptoms then developed fairly rapidly; 

 there was then profuse discharge from the eye, the 

 whole conjunctiva became inflamed, and later the 

 adjacent lymphatic vessels became affected ; the head on 

 the same side became greatly swollen, the disease 

 spread towards the orbital process, and the case was 

 shortly afterwards destroyed. In other cases it continues 

 indefinitely simply confined to the conjunctiva, or it 

 may spread down the lachrymal duct to the nose. 



When the nasal lesions are slight, there is an 

 absence of discharge from the nose, but later on a thin 

 fluid, mucous, muco-purulent, or sanious discharge 

 develops, presently accompanied by an unpleasant 

 odour from the breath. 



