37 



presence of the concretions, there should be no difficulty 

 in arriving at an accurate diagnosis. 



5. Botryomycosis is a disease due to the presence 

 of the Botryomyces equi, which get into the tissues and 

 bring about the formation of numerous subcutaneous 

 fibrous tumours, often seen under the saddle and collar. 

 However, they are easily differentiated by the absence of 

 cording and the fibrous appearance of the nodules, and 

 by the presence of the specific organism, which is easily 

 stained with aniline dyes, notably Loeffler's blue. 



6. The other diseases^ which may be confounded 

 with epizootic lymphangitis, are practically all those 

 which are mentioned in the differential dia^rnosis for 

 glanders, namely, strangles and its sequelae, variola 

 equina, follicular ulceration, stomatitis contagiosa pus- 

 tulosa, injuries of the nasal mucous membrane, carcino- 

 mata, sarcomata, actinomycosis, melanosis, and other 

 new growths, such as subcutaneous fibrous tumours, 

 warts, etc. : parasitic diseases, especially those affect- 

 ing the nasal cavity, urticaria, petechial fever, acne 

 contagiosa, vesicular eruptions on the genitals and 

 dourine. However, these diseases should be all easily 

 diagnosed by their characteristics, together with the 

 presence of their own particular organisms, if due to such, 

 and the constant absence of the characteristic symtoms 

 of epizootic lymphangitis and of the cryptococcus. 



Experimental Inoculation and Susceptible Species 



The disease is common to horses, mules, and 

 donkeys. Nocard and Leclainche state that mules are 

 more susceptible than horses, but my experience is that, 

 given the conditions the same, the susceptibility of 

 horses and mules is about equal, and both are probably 

 more susceptible than donkeys. 



Tokishige's experiments go to prove that the 

 disease may also affect cattle, but I am inclined to think 



