deep seated in the skin and which have not 

 yet come in contact with the air. 

 (4) Because inoculated into a healthy horse it 

 multiplies prodigiously at the seat of inocula- 

 tion where by degrees it gives rise to, first a 

 nodule, then a tumour, and then a tumefaction. 

 They then go on to state that the disease produced by 

 this cryptococcus is the same as that described by the 

 Frenchman, Chenier, several years before, under the 

 name of African or river farcy. 



Almost about the same time Bassi confirmed 

 these new discoveries and reported some interesting 

 clinical observations, and gave an account of some 

 attempts at experimental inoculations. Since then 

 * epizootic lymphangitis ' has formed the subject of 

 several essays by French veterinary officers (namely, 

 Jaubert, Quiclet, Debrade, Wiart, Peupion, Boinet, and 

 Chauvrat). Peuch gives a similar description of the 

 disease, and in 1891 Nocard also found the cryptococcus 

 in the pus and tissues, and pointed out the diagnostic 

 importance of the constant presence of the parasite, and 

 how easily it can be found ; he also called attention 

 to the existence in some cases of lesions on the mucous 

 membranes resembling glanders. 



Tokishige sat with a special Board of Commissioners 

 in 1 88 8, when they conducted experiments on this disease 

 in Japan, where it has been known for years under the 

 name of Japanese farcy. They reported having first found 

 a characteristic bacillus identical with Schatz-Loeffler's 

 bacillus, but in 1893 Tokishige found a second 

 pathological germ which he described as a kind of 

 ' saccharomyces,' and mentioned, at the same time, that 

 these organisms were found both in horses and cattle 

 presenting symptoms of Japanese farcy. According to 

 this writer the disease has been known in Japan under 



