38 DISEASES OF SWINE AND OTHER ANIMALS. 



Ociohcr 4, — Pig- A in first-raio hoaltli. Pig' a little more lively ; lias 

 fair appetite, but is not as greedy as formerly. 



October o. — Pig A in line condition, and all riglit in every respect. 

 Pig" C sliivers, and sneezes again a good deal, but does not show any 

 other perceptible symptoms of disease, except some ernptions bcLind 

 tlie ears, and on tlic external surface of the same. 



October G. — Pig' A all right in every respect. Pig C about the same as 

 preceding' day. 



October 7. — Pi.g A perfectly healthy. Pig' C has good appetite, and 

 T\ith the exception of its coat of hair being a little rougher than usual, 

 does not show any plain symptoms of disease. 



Made two post-mortem examinations of pigs ■which had died of swine- 

 plague at Mr. Hossack's place, five miles southwest of Champaign. In 

 the evening I examined microscopically the blood-serum or exudations 

 of the diseased lungs of one of Mr. Hossack's pigs, and found normal 

 red blood-corpuscles, numerous bacillus-germs in all stages of develop- 

 ment — single, budding, budded or double, and aggregated into clus- 

 ters — and some developed hacilU suis. 



October 8. — Pig A all right. Pig C shivering again. In the forenoon 

 I filtered some of the blood-serum of the diseased lungs of Mr. Hossack's 

 pig through eight filters — the very finest used in the chemical labora- 

 tory of the I. I. University — for the iiurj^ose of freeing the serum 

 from the bacilli and bacillus-germs ; but notwithstanding that I have 

 taken all possible precautions, the filtrate, which was almost limpid, 

 still contained, as examined under the microscope, a great many 

 bacillus- germs. I preserved it in a vial with a tight-fitting ground-glass 

 stop. 



October 9. — Pig A healthy. Pig C has fair appetite, but is not greedy. 

 I filtrated the filtrate once more through two filters, and obtained a 

 limpid fluid, which, however, at a microscopic examination, was found 

 to still contain some bacillus-germs. Preserved the filtrate again in a 

 clean vial, with a perfectly-fitting ground-glass stop. 



October 10. — Pig A healthy. Pig C eats its food, but is rather slow 

 at it. 



October 11. — Pig A healthv. Pig C about the same as on preceding 

 day. 



October 12. — Pig A healthy; \:ig C, no perceptible change. 



October 13. — Pig A all right in every respect ; pig C does not show 

 any i^lain symptoms of disease in the morning, but is sneezing again in 

 the evening. 



October 11. — Pig A in perfect health; pig C sneezes a good deal, but 

 has fair appetite. Took uj) again the filtrated blood-serum, and find- 

 ing, on examination under the microscope, that the bacillus-germs had 

 changed to bacilli (see drawing XI, figs. 1 and 2), I filtrated the same 

 again through four i)apers. IJr. Prentice and myself examined the fil- 

 trate obtained under the microscope (850 diameters), and neither of us 

 being able to discover any bacillus-germs, I inoculated pig A on the left 

 ear with the filtrate in the same manner in which the other pigs had 

 been inoculated. IMade two punctures, but used a needle a trille larger 

 than the one used before. 



October 15. — Pig A all right; no reaction Avhatever. Pig C sneezing, 

 but fair appetite. 



October IG. — Pig A perfectly healthy, and has remained so up to date 

 (iSTovembor 11th). It has never refused a meal, and has been always very 

 active and lively. It is now a very fine pig and in a first-rate condition. 

 (Made use of the same for another experiment on November loth.) Pig 



