1894.] MICROSCOPICAL JOURNAL. 305 



crease steadily for about six hours, although Cohuheim 

 states that it steadily and slowly increases for twelve 

 hours. At the beginning of this dilatation there was an 

 acceleration in the flow of the blood plainly noticeable, 

 but this, after lasting only about an hour, resulted in a 

 considerable retardation of the flow, the vessels still re- 

 maining dilated. 



After an hour and sometimes in the smallest capilla- 

 ries, much sooner, pulsation became evident and the 

 current of blood so slow that in the small veins and ca- 

 pillaries, the individual corpuscles became distinguish- 

 able. They can first be distinguished in the veins. In 

 two of my observations, this dilatation took place and 

 subsided without any of the other phenomena of inflam- 

 mation occuring, but, afterwards, a second dilatation 

 with slowed stream came on slowly, which was constant, 

 lasting as long as the cause operated. This last dilata- 

 tion was, no doubt, the vascular change of the inflam- 

 mation due to the irritation. 



Returning to the time when the corpuscles are first to 

 be distinguished, the following phenomena were observed, 

 useing now a one-sixth objective. As the blood stream be- 

 came slower, white corr)Uscles or leucocytes were seen in 

 the plasmatic layer in the smaller veins, rolling along 

 sticking here and there, coming to a stand-still for a few 

 seconds, then rolling on again, and at last often sticking 

 fast to the vessel wall, resisting all attempts of the cur- 

 rent to dislodge them. 



A vessel at this time presents the following appearance, 

 the white corpuscles being scattered here and there along 

 the vessel wall, while the central canal of the vessel, en- 

 closed on each side by the plasmatic layer in which the 

 leucocytes lie is filled with the red corpuscles which can 

 be distinguished very readily as the stream gets slower 

 and slower. One of two things now generally occurred, 

 either the leucocytes continued to accumulate on the 



