THE SLEEPING SICKNESS 



183 



by Leishman, in cases of a peculiar Indian fever, are 

 very probably of this nature, as are also similar bodies 

 recently described in Delhi sore. On the whole, it may 

 safely be said that the researches of Dr. Schaudinn, of 

 which only a preliminary account has yet been published, 

 have widely modified our conceptions as to these blood- 

 parasites, and must lead to important discoveries in 

 regard to diseases caused by them in mammals and 

 in man. 



The facts that wild game serve as a tolerant reservoir 

 of trypanosomes for the infection of domesticated animals 



Male Trypanosoma Ziemanni, giving rise 

 by nuclear division to eight spermatozoa 

 or microgametes. From the stomach of 

 the gnat (Culex). 



Each of these penetrates and fuses with 

 the substance of a female Trypanosome, 

 swallowed at the same time or already taken 

 in by the gnat. The fertilized animalculae 

 is the vermiform motile stage of Fig. 52, 

 A ; and so we return to the starting-point 

 of the cycle (after Schaudinn). 



FIG. 56. 



by the intermediary of the tsetze fly, and that native 

 children in malarial regions act the same part for the 

 malarial parasite and mosquito, suggest very strongly 

 that some tolerant reservoir of the sleeping-sickness 

 trypanosome may exist in the shape of a hitherto unsus- 

 pected mammal, bird, or insect. The investigation of 

 that hypothesis and the discovery of the reproductive and 

 secondary forms of the mammalian trypanosomes are the 

 matters which now most urgently call for the efforts of 

 capable medical officers. But we must not be sanguine 

 of rapid progress, since men of the scientific quality 



