6 4 



THE TUBERCULIN THERAPY. 



employment of B. E. can also be affected without producing any reaction, 

 although this is somewhat more difficult. 



The dosage scheme advised by Bandelier and Roepke is as follows: 



i/iooo, 2/1000, 3/1000, 7/1000, 10/1000 mg., 



15/1000, 2/100, 3/100, 5/100, 7/100, 10/100 mg., 

 At intervals of i to 2 days; 

 15/100, 2/10, 3/10, 5/10, 7/10, 10/10 mg., 



At intervals of 2 to 3 days; 

 12/10, 15/10, 2, 2 1/2, 3, mg., 



At intervals of 3 to 4 days; 



4, 5, 6, 7, 8, 9, 10 mg., 

 at 4 to 6 to 10 days intervals. 



In susceptible patients, it is best to increase the dosage only by one-half 

 mg. even when large doses are administered. Ten mg. B. E. represents 

 the maximal dose. 



The author himself follows a different scheme from that of Bandelier 

 and Roepke. The injections are given less frequently, only about once a 

 week, but the dose is always increased twofold, fivefold and even tenfold 

 without any excessive reactions. 



Fever is obtained much less often with new tuberculin than with T. The 

 reaction usually is in the form of lassitude, nausea, weakness, insomnia, etc. 



The treatment with new tuberculin is particularly favorable in cases 

 where a low continuous fever is present. It also is more potent in destroying 

 the bacilli of the sputum. The author therefore prefers this, especially the 

 B. E. to all other tuberculin preparations. Bandelier and Rcepke have also 

 obtained gratifying results with the B. E. therapy as is evident from the 

 following statistics of 205 patients treated at the sanatorium at Kottbus. 



