434 INHERITANCE AND DEVELOPMENT 



ganizcd bt>dics. It is true that we may trace in organic nature long 

 and finely graduated series leading upward from the lower to the 

 higher forms, and we must believe that the wonderful adaptive mani- 

 festations of the more complex forms have been derived from simpler 

 conditions through the progressiva operation of natural causes. But 

 when all these admissions are made, and when the conserving 

 action of natural selection is in the fullest degree recognized, we can- 

 not close our eyes to two facts : first, that we are utterly ignorant of > 

 the manner in which the idioplasm of the germ-cell can so respond | 

 to the influence of the environment as to call forth an adaptive \ 

 variation ; and second, that the study of the cell has on the whole '. 

 seemed to widen rather than to narrow the enormous gap that sepa-. 

 rates even the lowest forms of life from the inorganic world. 



I am well aware that to many such a conclusion may appear reac- 

 tionary or even to involve a renunciation of what has been regarded 

 as the ultimate aim of biology. In reply to such a criticism I can 

 only express my conviction that the magnitude of the problem of 

 development, whether ontogenetic or phylogenetic, has been under- 

 estimated ; and that the progress of science is retarded rather than 

 advanced by a premature attack upon its ultimate problems. Yet 

 the splendid achievements of cell-research in the past twenty years 

 stand as the promise of its possibilities for the future, and we need 

 set no limit to its advance. To Schleiden and Schwann the present 

 standpoint of the cell-theory might well have seemed unattainable. 

 We cannot foretell its future triumphs, nor can we doubt that the 

 way has already been opened to better understanding of inheritance 

 and development. 



LITERATURE. IX 



Barfurth, D. — Regeneration und Involution: Merkel u. Bonnet, Ergeb., l.-WW. 



1891-99. 

 Boveri, Th. — Ein geschlechtlich erzeugter Organismus ohne mlitterliche Eigen- 



schaften : Sitz.-Ber. d. Ges.f. Morph. und Fhys. in M'unchcn, V. 1889. See 



also Arch. f. Entiv. 1895. 

 Brooks, W. K. — The Law of Heredity. Baltimore. 1883. 

 Id. — The Foundations of Zoology. N'eiv York, 1899. 



Davenport, C. B. — Experimental Morphology: I.. II. Neiu York, 1897, 1899. 

 Driesch, H. — Analytische Theorie der organischen Entwicklung. Leipsig. 1894. 

 Id. — Die Localisation morphogenetischer Vorgange : Arch. Entii'.,W\l. i. 1899. 

 Id. — Resultate und Probleme der Entwickelungs-physiologie der Tiere : Merkel 11. 



Bomiet, Ergeb., VIII., 1898. (Full literature.) 

 Herbst, C. — Uber die Bedeutung der Reizphysiologie fiir die kausale Auffassung 



von Vorgangen in der tierischen Ontogenese : Biol. Centralb., XIV'., XV^ 



1894-95. 

 Eertwig, 0. — Altere und neuere Entwicklungs-theorien. Berlin. 1892. 



