EXTRACT IX. 



THE RELATIONSHIPS OF THE INCIDENCE OF ORGANIC 

 DISEASE TO THE DISTRIBUTION OF THE SYSTEMIC 

 NERVOUS SYSTEM. 



WE have already traced the incidence and manner of 

 manifestation of exanthematous and skin disease generally 

 to the manner of the terminal distribution of the systemic 

 nervature in relation to the other structural elements of 

 the skin, and have satisfied ourselves that it is almost all- 

 important therein, and we have now become satisfied that 

 the incidence and distribution of many affections of the 

 voluntary musculature, as well as of much organic disease 

 throughout the viscera, but more especially of the tissues 

 belonging to these viscera that are to any extent inner- 

 vated by the systemic nervature, are similarly determined. 



Thus the muscular system generally, owing to its 

 intimate materio-dynamic relationships with the central 

 nervature, is necessarily dependent for the origin and 

 progress of the main part of the disease to which it is 

 liable, to interferences with the processes of neuro-muscular 

 nutrition and neuro-muscular innervation, varying from 

 the extreme of the complete negation of myopathy to the 

 extreme of muscular hypertrophy in incidence, and from 

 the affection of single muscles to the wholesale affection 

 of the entire musculature. 



We mean to allude here more especially to the incidence 

 of organic disease of the heart and its dependence on 

 interferences with the neuro-muscular and central connec- 

 tions of the brain, cord, pneumogastric nerves, and heart. 



