ON RESPIRATION 515 



to the further opinion that circulatory immediateness and 

 availability are here the counterparts of each other, and 

 therefore, instead of being accidental and negligible, these 

 contiguous textural and organic arrangements must be 

 regarded as important structural features and parts of a 

 great biological design, the full proportions and beauty of 

 which are still hid from view, although, when seen from 

 certain points, it becomes " dimly visible " and profoundly 

 suggestive. 



The physiological results of cephalic blood aeration 

 and oxygenation must thus involve local chemical and 

 physical changes of an importance to the brain, and 

 connected nervous system, comparable in many respects 

 to those effected by pulmonary aeration and oxygenation 

 in the metabolism of the body generally, and, therefore, 

 the integrity of the local anatomical structures and their 

 functional wholeness become essential in relation to the 

 proper performance of man's highest psychological and 

 neural work. The so-called trivial affections of these 

 somewhat neglected air-chambers and subsidiary respira- 

 tory regions thus become morbid entities of great 

 importance, whose treatment it behoves us to place on 

 a more scientific basis than that on which we have 

 hitherto been content to apply it. 



