782 MICROBIOLOGY OF DISEASES OF MAN AND DOMESTIC ANIMALS 



It is a chronic inflammatory process found most commonly in the 

 foot, occasionally in the hand but very rarely elsewhere. It is charac- 

 terized by swelling and irregular deformities of the part with the 

 occurrence of sinuses whence there is a purulent discharge containing 

 granules suggesting those of actinomycosis. These granules may be 

 whitish, yellowish, reddish, or black in color. 



The causative organism is generally regarded as a fungus. It 

 is not unlikely that some cases of the disease may be confused with 

 actinomycosis. Several different molds have been described, some of 

 which have been classed as Aspergilli, while others have been given new 

 names. It is probable that, while the disease is a fairly well-marked 

 clinical entity, the etiological agent varies in different localities. 



Successful inoculation of the monkey with the white variety and of 

 pigeons with the black variety has been recorded. 



MYCOTIC LYMPHANGITIS* 

 Saccharomyces jarciminosus\ 



The disease caused by this yeast-like fungus has been called Japa- 

 nese farcy, epizootic lymphangitis, and mycotic lymphangitis. This 

 disease was first recognized in the United States in 1907. It has already 

 been found in Pennsylvania, Iowa, California, and North Dakota. 



Saccharomyces farciminosus produces a slow, chronic, contagious 

 disease of horses and mules. Cattle appear susceptible but rarely 

 show clinical symptoms of infection. 



This Saccharomyces involves especially the superficial lymphatic 

 vessels and glands, but internal organs are occasionally affected. 

 The disease is essentially local, constitutional disturbances being slight. 

 The disease produced is fatal in about 10 to 15 per cent of cases affected 

 but is much more serious than these figures would indicate. Other 

 horses that do not die are rendered useless for service, the sale value 

 being ruined in many cases. 



The lesions produced by this parasite resemble most closely the 

 farcy form of glanders but may be easily distinguished by quite different 

 ulcers. The pus is thick, creamy, and usually yellow, whereas the pus 



* Prepared by M. H. Reynolds. 



t Work done by Paige, Frothingham and Paige, Meyer and others raises questions concern- 

 ing specific etiology and proper classification, but it is deemed wise to continue this recognition 

 and classification for the present. Various authorities classify thj organism as cryptococcus, 

 blastomyces, etc, 



