898 MICROBIOLOGY OF DISEASES OF MAN AND DOMESTIC ANIMALS 



Oroya fever and Verruga were different stages or manifestations of a 

 single infection. Verruga is, however, readily transmitted to lower 

 animals. The mode of transmission of Oroya fever has not been 

 conclusively determined. 



ANAPLASMOSIS 



In a pernicious anaemia of cattle, and at times in babesiasis, the red 

 blood corpuscles contain minute, deeply stained, rounded bodies. These 

 are frequently in pairs and are commonly situated near the margin 

 of the cell so that they have been given the name Anaplasma marginale 

 (Theiler), by those who are convinced of their parasitic nature. They 

 have also been found in other domestic animals and similar structures 

 are found normally in all individuals of certain species, as for example, 

 the mouse. Since the bodies of this general appearance which occur 

 in normal animals are evidently to be regarded as nuclear material 

 certain investigators are inclined to doubt the parasitic nature of 

 Anaplasma. 



SARCOSPORIDIA (Balbiani) 



Different species of this order are frequent parasites of all the 

 domestic animals, of mice and, occasionally, of man. Mice are killed 

 by them and it is possible that they may produce ill effects in men and 

 domestic animals but no definite disease is associated with their 

 presence. Though they may occur in any part of the body, they are 

 most numerous in certain muscles, such as those of the larynx and 

 oesophagus, which are near the alimentary canal. For this reason it 

 seems possible that they may enter the bodies of their hosts with food, 

 but our knowledge of their life history is incomplete. 



HAPLOSPORIDIA (Caullery and Mesnil) 



One unimportant parasite, Rhino sporidium kinealyi, belonging to 

 this order is parasitic in man. It has been found in small tumors of 

 the nose and external ear. A few cases have been reported from Asia 

 and from North and South America. In the tumors cysts occur 

 which are filled with spores. 



