The Bodies of Negri 421 



spinal ganglia of human beings or animals dead of rabies, 

 by Mann's methylene-blue and eosin method, it was possi- 

 ble to demonstrate in the interior of the nerve-cells of their 

 protoplasmic process red colored, rounded bodies, measuring 

 4 to 10 [i, as a rule, though varying from i to 25 /u. In ex- 

 perimental infections under the dura they were most num- 



Fig. 133. Negri bodies. Cells from Ammon's horn impression of 

 cow 133, dried and fixed with gentle heat and stained with saturated 

 alcoholic eosin and Lomer's alkaline methylene-blue. Drawn with one- 

 twelfth oil immersion. Oc. 3 (Frothingham). 



erous in the hippocampal convolution. These bodies have 

 now become known as Negri bodies. 



The careful studies of Williams and Lowden* convince 

 them that the Negri bodies are protozoan organisms and 

 that their presence is pathognomonic of rabies. 



At the State Live-stock Sanitary Board of Pennsylvania, 

 Reichel and Englej stain Negri bodies with the following: 



* ''Jour. Infectious Diseases," in, 452, 1906. 

 t Personal communication. 



