Lesions 811 



Lesions. The degree of chemotactic influence exerted 

 by the organism seems to depend upon the tissue affected, 

 upon the peculiarity of the animal, and upon the virulence 

 of the organism. When an animal is but slightly suscepti- 

 ble, and especially when the tongue is affected, the disease 

 is characterized by the formation of cicatricial tissue 

 "wooden tongue." If, on the other hand, the animal be 

 highly susceptible and the jaw-bone affected, suppuration, 

 with the formation of abscesses, osteoporotic cavities, and 

 sinuses, are apt to be noticed. This form of the disease is 

 called "lumpy jaw" in cattle. 



Before the nature of the affection was understood it 

 was confounded with diseases of the bones, especially osteo- 

 sarcoma. 



From the tissues primarily affected the disease spreads 

 to the lymphatic glands, and eventually to the lungs. Israel 

 has pointed out that certain cases of human actinomycosis 

 begin in the peribronchial tissues, probably from inhalation 

 of the fungi. 



But few cases recover, the disease terminating in death 

 from exhaustion or from complicating pneumonia or other 

 organic lesions. 



