QUESTIONS 93 



What peculiarity in the distribution of salts in the corpuscles and in the 

 plasma? 



Describe the process of clotting. 



How is the buffy coat produced? 



Give the chemistry of clotting. 



How is fibrin ferment obtained? 



How has it been shown that fibrin ferment is normally not present in 

 the blood? 



Give proof as to the origin of the fibrin ferment. 



How may intravascular clotting be produced? 



Explain the "negative phase" produced by the injection of ferment into 

 the vessels of an animal. 



What experiment shows that the epithelial lining of the vessels normally 

 prevents clotting of the blood? 



How much blood may be lost without fatal results? 



Why is the injection of sodium chloride solution beneficial after severe 

 hemorrhage? 



Why is the transfusion of blood dangerous? 



What is meant by the globulicidal and toxic actions of the blood? 



What is defibrinated blood? 



What is the reason for the belief that two bodies are concerned in hemo- 

 lysis by immune serum? 



What evidence is there against Bordet's conception of a sensitizing 

 substance ^n the hemolytic action of serum? 



Give a brief exposition of Ehrlich's side-chain theory. 



Differentiate between receptors of the first, second, and third order. 



Explain the formation of antitoxin. 



What are agglutinins, precipitins, and opsonins? 



What is Metchnikoff's theory of phagocytosis? 



