BACILLUS TUBERCULOSIS 39 



material and well-stained peripheral fringe of nuclei. 

 As to the origin of these giant cells and the his- 

 tology of tubercle, it is not within the province of 

 this book to speak. Within the giant cell and 

 collected near the nuclei are seen numerous bacilli. 

 The general arrangement is peripheral and radiate. 

 In the tissue around the giant cell may be observed 

 portions of the tubercle where necrotic changes 

 are commencing, as shown by the poor and partial 

 staining of the nuclei and other portions, where 

 this change is so complete that the staining power 

 of the tissue is completely absent. 



