LEPROSY (BACILLUS LEPR.E) 45 



and the large cell to which, more particularly, the 

 name Lepra cell is given. The latter are commonest 

 in the older tissues. These bacilli do not extend 

 beyond the Malpighian layer. The appearances 

 presented by the skin are reproduced in affected 

 mucous membranes, especially in the la,rynx- 

 Affected nerves show an interstitial neuritis with 

 large numbers of bacilli on the connective tissue. 

 The internal organs, especially the liver, spleen, and 

 testicle, are studded with granulomata crowded 

 with the characteristic microbe. 



That the disease is infectious to some extent 

 there can be no doubt, but the mode of origin and 

 the exact methods by which it is spread are still 

 unknown. 



