GONORRHOEA. 301 



This author states, however, that it is not trans- 

 mitted with certainty, so that the rabbit cannot be 

 used as a test in doubtful cases, inasmuch as posi- 

 tive results alone are of value. In successful cases 

 the lesions resemble those of purulent infection, 

 and caseous deposits form at the point of inocula- 

 tion. It is only exceptionally that lesions are 

 found in the lungs and nasal mucous membrane. 



GONORRHOEA. The constant presence of micro- 

 cocci in the pus of specific urethretis has now been 

 verified by numerous observers. Neisser of Bres- 

 lau is said to have first observed them, and in a 

 paper published in 1879 he advances evidence in 

 favor of the belief that they are the cause of the 

 specific virulence of the fluid in which they are 

 found. According to this author and to Weiss 

 (1880), these micrococci are found in gonorrhoeal 

 pus from the male urethra, and in that from the 

 female vagina, in blenorrhcea neanotorum, and in 

 gonorrhoeal ophthalmia. On the other hand, Neisser 

 failed to find them in pus from other sources 

 chancres, bubo, etc. Weiss also confirms Neisser 

 in this, and states that they are not present in the 

 secretions of simple urethretis. Eecently this 

 subject has been investigated in a painstaking 

 manner by Mr. A. S. Keyser (medical student in 

 the University of Maryland). His observations 

 fully confirm Neisser as to the constant presence 

 of the " gonococcus " in specific purulent dis- 

 charges, and its absence from non-specific pus 

 from various sources. 



