326 BACTERIA IN INFECTIOUS DISEASES. 



by the author referred to, differs from ordinary 

 malarial fevers intermittents and remittents 

 which also prevail in Italy, in the essential par- 

 ticular that it is an infectious disease, and may be 

 transmitted to the lower animals ; as well as in the 

 fact that it is a continued rather than a paroxysmal 

 fever. 



The writer has long suspected that the continued 

 pernicious fevers of the Roman Campagna, and of 

 other parts of Italy, differ essentially from the or- 

 dinary intermittents and remittents of this country, 

 and that, while there is undoubtedly a malarial 

 element, in a certain proportion of the cases at 

 least, there is another etiological factor to which 

 the continued and pernicious form of development 

 manifested by the morbid phenomena must be 

 ascribed. We know that malaria may be associ- 

 ated with the specific poisons of typhoid and of 

 yellow fevers in such a way as to produce atypical 

 forms of these diseases, and it seems not impro- 

 bable that the Roman fever is in truth one of these 

 mixed or hybrid forms of disease. In this case 

 the bacillus of Klebs and Tommasi-Crudeli, if it 

 has any etiological import, is probably the factor 

 to which the continued and pernicious form of this 

 fever must be ascribed, rather than the malarial 

 germ, which the authors named had undertaken 

 to discover. 



Professor Ceri's experiments relating to the 

 germicide power of quinine are extremely impor- 

 tant and interesting. But it is well to remember 



