328 BACTERIA IN INFECTIOUS DISEASES. 



opment of the Bacillus malarice should be tested 

 as a check on the conclusions which may be too 

 hastily drawn from Professor Ceri's experiments 

 with quinine. 



Second. It is not impossible that the pernicious 

 malarial fevers of Italy may differ essentially from 

 the ordinary remittents and intermittents of this 

 country, and that their continued form is due to a 

 septic complication, which may result from invasion 

 of the blood by a pathogenic organism peculiar to 

 that country or to the tropical and semi-tropical 

 regions where pernicious fevers are most prevalent. 



Third. Fat-granules are found in the white 

 corpuscles of the blood of yellow fever, which 

 disease resembles the pernicious malarial fevers in 

 many particulars, which bear so strong a resem- 

 blance to the spores of bacilli that a mistake might 

 easily be made. 1 (See p. 425.) Several of the 

 observers named found spores " included in the 

 white blood-corpuscles, which were sometimes so 

 numerous as to seem to fill them completely." 



Fourth. No great significance can be attached 

 to the finding of bacterial organisms post morion 

 in the blood and tissues, especially in warm cli- 

 mates, unless the examination is made intntcdmldf/ 

 after death. And even then we must admit the 

 possibility that such organisms may migrate from 

 the intestine, where they are always present in 

 abundance, during the last hours of life, when the 

 circulation is feeble, and the vital resistance of the 



1 Compare Fig. 3, Plate X., and Fig. 3, Plate III. 



