344 BACTERIA IN INFECTIOUS DISEASES. 



A syringeful of blood from thte animal killed a 

 second rabbit in forty hours. Rabbit No. 3 was 

 killed in fifty-four hours by three drops of blood 

 from No. 2 ; one drop from No. 3 killed No. 4 in 

 ninety-two hours; one-tenth of a drop from No. 

 4 killed No. 5 in one hundred and twenty-five 

 hours. The pathological appearances in this se- 

 ries of rabbits were similar to those noted in 

 the first, viz. : 



" Local purulent cedematous infiltration of the sub- 

 cutaneous cellular tissue ; metastatic deposits in the 

 lungs and liver ; swelling of the spleen and peritonitis. 

 These appearances harmonize so closely with those 

 commonly designated as pyaemia that I do not hesitate 

 to use that term for the disease under consideration. 



" On microscopic examination micrococci are found 

 in great numbers everywhere throughout the body, and 

 more especially in parts which have undergone altera- 

 tions visible to the naked eye. These micrococci are, 

 for the most part, single or in pairs, and their meas- 

 urement is therefore difficult. Ten measurements of 

 pairs of micrococci differed but little from each other, 

 and gave .25 /JL. as the average diameter of a single 

 individual." 



It will be noticed that this is much less than the 

 size of the oval micrococcus which produces septi- 

 caemia in rabbits. 



"As regards size, therefore, they stand midway 

 between the chain-like micrococcus of the progressive 

 gangrene of the tissues and the zoogloea-forming micro- 

 coccus of the cheesy abscesses of rabbits. Their relation 

 to the blood-vessels can be best seen in the renal capil- 



