YELLOW FEVER. 433 



granulations. These are from 5 to 12 /x in diameter. 

 These large granulations were those which first attracted 

 attention in the urine of the patients first examined, and 

 since found in the cellular tissues, serum of blisters, 

 and other points of the organism. There were in the 

 urine threads, evidently mycelia, some so large as to 

 cover the whole field of view, others smaller ; and, 

 besides, there were abundant fragments, of various forms 

 and dimensions. Some were more delicate and of a 

 cellular aspect ; others more compact and larger, of a 

 brilliant yellow color and of fatty aspect ; some of 

 a more reddish color ; others emerald green ; still others, 

 but much more rare, of a blue color. Their diameters 

 varied from 2 to 20 /*. Cells were frequently encountered 

 completely empty, of rounded or pyriform shape and 

 variable dimensions. Many of these cells were not entirely 

 empty, but contained a red or yellow granular material, 

 similar to the points observed in the gold-stone." 



The writer has ventured to italicize this descrip- 

 tion of these partially empty cells, as it recalls to 

 his mind a story told him by his friend, Dr. J. J. 

 Woodward, of the United States Army, whose skill 

 as a microscopist is pretty generally recognized, 

 both in this country and in Europe. 



Dr. Woodward states that several years since a 

 distinguished (?) professor from one of the Western 

 cities came to Washington to show him the germ 

 of malarial fever which he had recently discovered. 

 An examination of his specimens showed that the 

 supposed alga (cryptococcus) was nothing more nor 

 less than the little depressions in the surface of the 

 glass slide upon which his material was mounted, 



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