282 BACTERIA IN INFECTIOUS DISEASES. 



and friable. When incised, bright red blood es- 

 capes, in the earlier stage of development, later 

 a liquid resembling venous blood, and at last a 

 frothy serum. The tumor may be deeply buried 

 in the muscles, and may then escape observation. 

 Death usually occurs within 36 to 48 hours after 

 the appearance of the first symptoms. The dis- 

 ease is always fatal. After death the body rap- 

 idly becomes inflated by an accumulation of gas 

 in the abdomen, in the veins, and in the cellular 

 tissue. One or more bloody tumors are found 

 among the muscles, which, when incised, present 

 a characteristic black color, are very friable, and 

 infiltrated with gas. The digestive organs are 

 usually entirely healthy, and the liver and spleen 

 are normal in appearance although they contain 

 the microbe in abundance. 



Symptomatic anthrax is not readily communi- 

 cated by small amounts of virus. In a few cases 

 only have successful inoculations been made with 

 the pulp of diseased glands in small quantity. 

 But larger amounts of the infectious material 

 produce the characteristic tumors. In suscepti- 

 ble animals a few drops of blood, or muscle pulp, 

 forced into the cellular tissue produces fatal re- 

 sults. Intra- venous injections of as much as 2.6 

 c.c. of the pulp from a tumor are tolerated by the 

 calf, sheep, and goat. A mild sickness results 

 from such an injection, and in rare cases death 

 occurs. The guinea-pig is susceptible, but the 

 rabbit is not. The microbe is said to present 



