320 



BACTERIA IN INFECTIOUS DISEASES. 



found either at the poles, or in the middle of the seg- 

 ment, serves as a mark of distinction between this and 

 other pathological bacilli. 



44 Following Klebs and 

 Tommasi-Crudeli, Mar- 

 chiafava and Cuboni, in 

 Italy, 1 studied the blood 

 of men ill with malaria. 

 In this they found spores 

 and bacilli which they 

 declared to be identical 

 with those described by 

 the former. The spores 

 included in the white 

 blood - corpuscles were 

 sometimes so numerous 

 as to seem to fill them 

 completely. Similar stud- 

 ies on malarial patients 

 by Lanzi, and again by 

 Peroncito, led to the same conclusions. 



44 Succeeding these, Marchand published in Virchow's 

 4 Archiv ' 2 some observations really made in 1876, 

 whence he concluded that there exists in the blood, in 

 the cold stage of intermittent fever, mobile and flex- 

 ible rods, presenting slight swellings at their ends, and 

 sometimes also at the middle. These end-swellings he 

 thought also might be of the nature of spores. 



" More recent still are the elaborate experiments of 

 Professor Ceri, of Camerino, Italy, published in the 

 4 Archiv fur experimentelle Pathologic.' 3 These con- 



1 Arcliiv fiir experimentelle Pathologic, Vol. XIII. 



2 Vol. LXXXVIII. p. 104, April, 1882. 



3 Vols. XV. and XVI. 1882. 



Fig. 14. 



Bacillus malaria in blood drawn during 

 life from the spleen of a person suffering 

 from malarial fever. (From Cuboni and 

 Marchiafava, in Klebs' Archiv, etc., 1881.) 

 X. />. These bacilli were found in one case 

 only . 



