PYAEMIA IN RABBITS. 343 



/ ' 



IX., and also p. 359.) Leyden has demonstrated the 

 presence of numerous micrococci corresponding 

 with those described by Friedlander in exudation 

 fluid obtained during life from a patient suffering 

 from severe croupous pneumonia. The fluid was 

 withdrawn by means of a hypodermic syringe. 

 Gunther. also, has obtained the same result from 

 an exploratory puncture of hepatized lung. On 

 the other hand, negative results were obtained by 

 Leyden in two milder cases of pneumonia in which 

 fluid was withdrawn from the inflamed lung; and 

 in an epidemic described by Kiihn, search for 

 micro-organisms gave a negative result. 



IN KABBITS, Koch. After failing to 

 produce a general infection in rabbits by the 

 injection of putrid blood, Koch succeeded with a 

 fluid obtained by macerating for two days in dis- 

 tilled water a bit of the skin of a mouse. The 

 animal died at the end of one hundred and five 

 hours, and a purulent infiltration of the subcuta- 

 neous cellular tissue was found, extending from 

 the point of inoculation as far as the hip behind, 

 and to the middle of the belly below. The peri- 

 toneal cavity contained a turbid fluid, and its 

 walls were covered in places by white patches. 

 The liver was covered with a fibrinous exudation, 

 and presented a grayish mottled appearance ; upon 

 section it showed gray, wedge-shaped patches. In 

 the lungs were found dark red patches, the size of 

 a pea. 



