372 BACTERIA IN INFECTIOUS DISEASES. 



animal in thirty-seven hours, did not give rise to 

 the infectious form of the disease ; for a second 

 mouse, which was inoculated with blood from the 

 heart of the first, was not visibly affected. 



In a limited number of experiments by the 

 writer, in which his own saliva was injected into 

 animals other than the rabbit, the following results 

 were obtained : 



Injection of 4 c. c. into each of two small dogs pro- 

 duced local abscesses at the point of injection, but no 

 other noticeable results. A dog succumbed, however, 

 to an injection of 1 c. c. of serum from the cellular tis- 

 sue of a rabbit recently dead. 



Injection of 0.25 c. c. (each) into five chickens pro- 

 duced no result. 



Injection of 0.75 c. c. (each) into three guinea-pigs 

 proved fatal to two, one in three, and one in seven 

 days. 



Injection of 0.5 c. c. into five rats resulted fatally to 

 one only. 



These results correspond with those reported by 

 Pasteur, who found the guinea-pig less susceptible 

 than the rabbit; the chicken entirely insuscepti- 

 ble ; and the dog susceptible to injections of blood 

 from dead rabbits. 



The value of protective inoculations in this form 

 of septicaemia has been brought out accidentally 

 in the course of the writer's experiments ; and it 

 has been his intention to investigate this interest- 

 ing subject fully by the experimental method. 

 This he has not yet been able to do, and, conse- 



