120 STUDY AND IDENTIFICATION OF MOULDS 



S. blanchardi. Found in a jelly-like tumor mass of the abdomen. The budding 

 cells varied from 2 to 20/1. Probably identical with S. tumefaciens, reported 

 as the cause of a subcutaneous tumor about region of Scarpa's triangle. 

 Endomyces. Forms spores in the interior of filaments, or by ascus formation or by 

 chlamydospores (resistant spore-like structures with a thick membrane which 

 project from the extremities or sides of the hyphae as bud-like structures). 



E. albicans. The organism of thrush. It produces a false membrane, especially 

 on buccal surfaces, which is easily detached and beneath which the mucosa is 

 intact. Grows only in acid media. Hence propriety of alkaline treatment. 

 Cryptococcus. Reproduces by budding, but ascospore formation not observed. 

 Not a well-recognized genus. The diseases caused by it are termed blasto- 

 mycoses. 



C. Gilchristi. The cells are about i6/* in diameter and have a thick, double 

 contoured membrane. They reproduce by budding. The skin lesions resemble 

 various infectious granulomata and diagnosis rests on the finding of budding 



FIG. 40. Thrush fungus. (Kolle and Wassermann.) 



or sporulating cells. It may invade internal organs. Original cultures are 

 obtained with some difficulty and then best with LofHer's serum. Subcultures 

 grow readily. Potato is a good medium and on it we may have both mycelial 

 and yeast-like growth. Guinea-pigs can be inoculated subcutaneously. A 

 mould, somewhat similar, is the Coccidioides immitis of Ophuls. This has a 

 mycelial growth in tissues, this distinguishing it from the former fungus. The 

 infection frequently becomes generalized. The small bodies, about 3jw, in the 

 Molluscum contagiosum cells are thought by some to be yeasts. They are more 

 probably artefacts. Plimmer's bodies in cancer cells belong in this group. 

 They also are probably other than parasites. 



C. linguae pilosae. This is a more or less elongated yeast-like organism and sup- 

 posed to be the cause of black tongue, a benign affection of the lingual papillae. 



Gymnoascea. -Belonging to the family Gymnoasceae we have the 

 genera Trichophyton, Microsporum and Achorion. 



