96 ESSENTIALS OF BACTERIOLOGY. 



Koch's lymph is injected under the skin of one suffering with 

 a tubercular process, and in a few hours to a few days, a rise of 

 temperature, tightness about the chest, and exaggerated cough- 

 ing spells take place, the symptoms varying in intensity; 

 usually a secondary rise occurs on the following day. The 

 dose has been gradually increased until the reactions subsided, 

 and GOO milligrammes have then been borne without any reaction. 



On Lupus the process could be watched and was very char- 

 acteristic ; a peculiar redness after the first injection, and after 

 a few more injections scabs formed, and an apparent cure seemed 

 to be obtained, but relapses were common and but very few 

 authentic cures if any can now be had. 



Koch believed that the tuberculosis tissue was rendered 

 necrotic by this toxic principle, making the soil unfit for the 

 bacilli which then perished or were expectorated. 



Virchow dampened the excitement and ardor by showing a 

 great diffusion of fresh miliary tubercles in the bodies of persons 

 who had died and who had been treated with the lymph. Cool, 

 careful, and untiring study and time taken together will, we 

 trust, bring a happy solution and a genuine remedy. 



Lepra Bacillus. ( H a n sen . ) 



Origin. In 1880 Armauer Hansen declared, as the result of 

 many years' investigation, that he found a bacillus in all leprous 

 processes. 



Form. Small slender rods somewhat shorter than tubercle 

 bacilli, otherwise very similar in appearance. 



In the interior of the cell two to three oval spaces are usually 

 seen, not known if spores or otherwise. 



Properties. They are immotile, do not liquefy the nutrient 

 media. 



Growth. Bordoni-Uffreduzzi have obtained growths upon 

 blood serum to which peptone and glycerine had been added. 

 The growth is very slow, requiring about eight days at a tem- 

 perature of 37 C. 



Colonies. Small grayish round spots, under microscope ap- 

 pearing like a close-netted spider web around a firm centre. 



Stab Cultures. Show a waxy-like growth along the needle track. 

 /. They resist the decolorizing action of acids as the 



