114 ESSENTIALS OF BACTERIOLOGY. 



Stab Cultures. Along the needle-track small separate white 

 granules, one above the other, like a string of beads. 



Stroke Culture. On agar, transparent, almost invisible little 

 drops resembling dew moisture. 



Bouillon. They grow better here than in the other media, 

 remaining alive a longer period of time. 



Staining. Takes Gram's method and the other aniline stains 

 very readily. The capsule stained the same way as that of the 

 Friedlande-r bacillus. 



Pathogenesis. Rabbits and guinea-pigs, if subcutaneously in- 

 jected, die in the course of a couple of days with septicaemia. 

 (0.1 c.cm. of a fresh bouillon culture suffices.) 



Autopsy shows greatly enlarged spleen and myriads of bacilli 

 in the blood and viscera, the lungs not especially affected. If 

 injected per trachea, a pneumonia occurs. In man in 90 pel- 

 cent, of croupous pneumonia they are found and usually only 

 during the existence of the u prime juice" sputum, i. e., the first 

 stage. 



Fia. 60. 



/ ,x 



* 

 t 



Micrococcus tetragenus in sputum (tubercle bacillus also). 



They have also been found in pleuritis, peritonitis, pericarditis, 

 meningitis, and endocarditis. They stand in some intimate re- 

 lation with all infectious inflammations of the body. Their 

 presence in healthy mouth secretion does not speak against it, it 



