28 BACTERIOLOGY. 



in erysipelatous inflammations secondary to injury by 

 Wilde, Orth, von Recklinghausen, Luthomsky, Bill- 

 roth, Ehrlich, Fehleisen, and others, agreeing that in 

 these conditions micro-organisms could always be de- 

 tected in the lymph-channels of the subcutaneous 

 tissues ; and through numerous experiments on ani- 

 mals the pathogenic character of the micro-organisms 

 found in erysipelas, suppuration from wounds, diph- 

 theria, puerperal fever, etc., was established by Oertel, 

 Huester, Birsch-Hirschfeld, Narsiloff, Classen, Letz- 

 erich, Leber, Frisch, Eberth, Klebs and others. 



The brilliant results obtained by Lister, in 1863 

 1870, in the antiseptic treatment of wounds, to prevent 

 or inhibit the action of infective organisms, exerted a 

 powerful influence on the doctrine of bacterial infec- 

 tion, causing it to be recognized far and wide and 

 gradually lessening the number of its opponents. 



The next important discovery was that of Ober- 

 meier, a German physician, who, in 1873, announced 

 having found in the blood of patients suffering from 

 relapsing fever a minute spiral, actively motile micro- 

 organism the spirochcete Obermeieri which is now 

 generally recognized as the specific infectious agent in 

 this disease. 



In 1877, Weigert and Ehrlich recommended the use 

 of the aniline dyes as staining agents in the micro- 

 scopical examination of micro-organisms in cover-glass 

 preparations. 



In 1878, Koch published his important work on 

 traumatic infectious diseases. 



Hausen, in 1879, reported the discovery of bacilli 

 in the cells of leprous tubercles, which, from subsequent 

 researches, are believed to be the cause of leprosy. 



