30 BACTEEIOLOG T. 



In 1882, Koch published his discovery of the tubercle 

 bacillus. 



The same year (1882) Pasteur published his in- 

 vestigations upon "rouget" or hog erysipelas. In 

 this year, also, his first communication upon rabies 

 appeared. 



In 1882, also, Loemer and Schiitz discovered the 

 bacillus of glanders. 



The cholera spirillum, or " comma bacillus/' was 

 discovered by Koch in 1884. 



The diphtheria bacillus was discovered during the 

 same year (1884) by Loemer, though it had been ob- 

 served by Klebs the year before (1883). 



Rosenbach, in 1884, by the application of Koch's 

 methods, fixed definitely the characters of the various 

 micro-organisms found in the pus from acute abscesses, 

 etc. 



The tetanus bacillus was also discovered in 1884 by 

 Nicolaier. Carle and Rattone showed that tetanus is 

 an infectious disease communicable to man by inocula- 

 tion. Kitasato, in 1889, obtained the bacillus in pure 

 cultures. 



In 1892, Pfeiffer and Canon independently discov- 

 ered a bacillus which is believed to be the specific 

 cause of influenza. 



In 1894, Kitasato, the Japanese bacteriologist, during 

 a visit to China, discovered the bacillus of the bubonic 

 plague. 



These include all the most important pathogenic 

 bacteria, the discovery of which is of special interest 

 to medical students and physicians. We cannot close 

 this brief historical review, however, of the progress of 

 our knowledge in this department of science, without 



