494 BACTERIOLOGY. 



tended honesty of his conclusions, it is my conviction 

 that they give undoubtedly too favorable a view of the 

 value of the serum. 



In the comparatively few cases of puerperal fever, 

 wound infection, scarlet fever, and bronchopneumonia 

 that we have seen under the treatment the apparent re- 

 sults have not been uniform. Only occasionally did 

 we see results which appeared to be distinctly due to 

 the serum. 



In a number of cases of septicaemia where chills had 

 occurred daily for days they ceased absolutely or 

 lessened under daily doses of 20 to 50 c.c. The 

 temperature, though ceasing to rise to such high eleva- 

 tions, did not average more than one or two degrees 

 lower than before the injections. The serum treat- 

 ment was kept up for four weeks. Some cases conva- 

 lesced; others after a week or more grew worse and died. 



In some cases the temperature fell immediately upon 

 giving the first injection of serum, and after subse- 

 quent injections remained normal, and the cases seemed 

 greatly benefited. As a rule, in these cases no strep- 

 tococci or any other organisms were obtained from the 

 blood. On bronchopneumonia, laryngeal diphtheria, 

 and in phthisis we have seen absolutely no effect. 



The results obtained here in New York by both 

 physicians and surgeons have not, on the whole, been 

 very encouraging. 



In some of the cases where apparently favorable re- 

 sults were obtained other bacteria than streptococci were 

 found to be the cause of the disease. We believe that 

 the following conclusions will be found fairly accurate : 



A single antistreptococcic serum protects healthy 

 rabbits from infection from most of the streptococci 

 obtained from human sepsis due to the streptococcus, 



